High throughput gene expression analysis identifies reliable expression markers of human corneal endothelial cells

Considerable interest has been generated for the development of suitable corneal endothelial graft alternatives through cell-tissue engineering, which can potentially alleviate the shortage of corneal transplant material. The advent of less invasive suture-less key-hole surgery options such as Desce...

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Veröffentlicht in:	PloS one 2013-07, Vol.8 (7), p.e67546-e67546
Hauptverfasser:	Chng, Zhenzhi, Peh, Gary S L, Herath, Wishva B, Cheng, Terence Y D, Ang, Heng-Pei, Toh, Kah-Peng, Robson, Paul, Mehta, Jodhbir S, Colman, Alan
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Analysis Anion Transport Proteins - genetics Anion Transport Proteins - metabolism Antiporters - genetics Antiporters - metabolism Autopsy Biology Biomarkers - metabolism Collagen Type VIII - genetics Collagen Type VIII - metabolism Cornea Corneal Keratocytes - cytology Corneal Keratocytes - metabolism Corneal Stroma - cytology Corneal Stroma - metabolism Corneal transplantation Developmental biology Donors Endothelial cells Endothelial Cells - cytology Endothelial Cells - metabolism Endothelium Endothelium, Corneal - cytology Endothelium, Corneal - metabolism Female Fibroblasts Gene Expression Gene Expression Profiling Gene sequencing Genes Genetic aspects Genomes Grafts Humans Male Markers Medicine Membrane Proteins - genetics Membrane Proteins - metabolism Middle Aged Mutation Organ Specificity Physiological aspects Primary Cell Culture Ribonucleic acid RNA Signal transduction Stem cells Stroma Surgery Therapeutic applications Thickness Tissue engineering Transplantation Transplants & implants
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