A high frequency of circulating th22 and th17 cells in patients with new onset graves' disease

T-helper (Th) 22 and Th17 cells are involved in the pathogenesis of autoimmune diseases. However, their roles in the pathogenesis of Graves'disease (GD) are unclear. This study is aimed at examining the frequency of peripheral blood Th22, Th17, and Th1 cells and the levels of plasma IL-22, IL-1...

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Veröffentlicht in:	PloS one 2013-07, Vol.8 (7), p.e68446-e68446
Hauptverfasser:	Peng, Di, Xu, Bingchuan, Wang, Ye, Guo, Hui, Jiang, Yanfang
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Analysis Antibodies Autoimmune diseases Blood CD4-Positive T-Lymphocytes - immunology Chemiluminescence Cytokines Cytometry Disease Enzyme-linked immunosorbent assay Enzymes Female Flow cytometry Gender Graves Disease - blood Graves Disease - immunology Helper cells Humans Hyperthyroidism Interferon Interferon-gamma - blood Interferon-gamma - immunology Interleukin 17 Interleukin 22 Interleukin-17 - blood Interleukin-17 - immunology Interleukins - blood Interleukins - immunology Laboratories Lymphocytes Lymphocytes T Male Medicine Middle Aged Pathogenesis Patients Peripheral blood Psoriasis Radioimmunoassay Rheumatoid arthritis Th1 Cells - immunology Th17 Cells - immunology Thyroid Thyroid gland Thyroid hormones Thyroid-stimulating hormone Thyroid-stimulating hormone receptors Thyrotropin - blood Thyrotropin - immunology Thyroxine Thyroxine - blood Thyroxine - immunology Triiodothyronine Triiodothyronine - blood Triiodothyronine - immunology Young Adult Zoonoses γ-Interferon
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