Gene expression profiles of metabolic aggressiveness and tumor recurrence in benign meningioma

Around 20% of meningiomas histologically benign may be clinically aggressive and recur. This strongly affects management of meningioma patients. There is a need to evaluate the potential aggressiveness of an individual meningioma. Additional criteria for better classification of meningiomas will imp...

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Veröffentlicht in:	PloS one 2013-06, Vol.8 (6), p.e67291-e67291
Hauptverfasser:	Serna, Eva, Morales, José Manuel, Mata, Manuel, Gonzalez-Darder, José, San Miguel, Teresa, Gil-Benso, Rosario, Lopez-Gines, Concha, Cerda-Nicolas, Miguel, Monleon, Daniel
Format:	Artikel
Sprache:	eng
Schlagworte:	Adaptor Proteins, Signal Transducing - genetics Adaptor Proteins, Signal Transducing - metabolism Adult Aged Aged, 80 and over Angiogenesis Apoptosis Benign Biology Biomarkers, Tumor - genetics Biomarkers, Tumor - metabolism Brain cancer Cancer therapies Chromosomes Cluster Analysis DNA microarrays Energy demand Female Gene expression Gene Expression Regulation, Neoplastic Gene regulation Genes Genetic engineering Genomics Humans Insulin Insulin-like growth factors LIM Domain Proteins - genetics LIM Domain Proteins - metabolism Male Medical prognosis Medicine Membrane turnover Meningeal Neoplasms - genetics Meningeal Neoplasms - metabolism Meningeal Neoplasms - pathology Meningioma Meningioma - genetics Meningioma - metabolism Meningioma - pathology Metabolism Metabolites Middle Aged Molecular Sequence Annotation Neoplasm Recurrence, Local - genetics Neoplasm Recurrence, Local - metabolism Nervous system Neuroblastoma NMR Nuclear magnetic resonance Oligonucleotides Real-Time Polymerase Chain Reaction Studies Subgroups Surgery Transcription Transcriptome Tumors Up-Regulation
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