Deep Sequencing the MicroRNA Transcriptome in Colorectal Cancer

Colorectal cancer (CRC) is one of the leading causes of cancer related deaths and the search for prognostic biomarkers that might improve treatment decisions is warranted. MicroRNAs (miRNAs) are short non-coding RNA molecules involved in regulating gene expression and have been proposed as possible...

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Veröffentlicht in:	PloS one 2013-06, Vol.8 (6), p.e66165-e66165
Hauptverfasser:	Schee, Kristina, Lorenz, Susanne, Worren, Merete Molton, Günther, Clara-Cecilie, Holden, Marit, Hovig, Eivind, Fodstad, Oystein, Meza-Zepeda, Leonardo A, Flatmark, Kjersti
Format:	Artikel
Sprache:	eng
Schlagworte:	1-Phosphatidylinositol 3-kinase Adenomatous polyposis coli Analysis Biology Biomarkers Biomarkers, Tumor - genetics Cancer Cancer metastasis Cluster Analysis Colon Colorectal cancer Colorectal carcinoma Colorectal Neoplasms - genetics Dihydrofolate reductase Female Gene expression Gene sequencing Genes Genomics Hazard identification Health aspects High-Throughput Nucleotide Sequencing - methods Hospitals Humans Informatics Male Medical prognosis Medical research Medicine Metastases Metastasis MicroRNA MicroRNAs MicroRNAs - genetics miRNA Non-coding RNA Patients Prognosis Proportional Hazards Models Real-Time Polymerase Chain Reaction Rectum Ribonucleic acid RNA Statistical models Studies Surgery Transcriptome Tumors
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