Combining mTOR inhibition with radiation improves antitumor activity in bladder cancer cells in vitro and in vivo: a novel strategy for treatment

Radiation therapy for invasive bladder cancer allows for organ preservation but toxicity and local control remain problematic. As such, improving efficacy of treatment requires radiosensitization of tumor cells. The aim of study is to investigate if the mammalian Target of Rapamycin (mTOR), a downst...

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Veröffentlicht in:PloS one 2013-06, Vol.8 (6), p.e65257-e65257
Hauptverfasser: Nassim, Roland, Mansure, Jose Joao, Chevalier, Simone, Cury, Fabio, Kassouf, Wassim
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Sprache:eng
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