Characterization of hair follicle development in engineered skin substitutes

Generation of skin appendages in engineered skin substitutes has been limited by lack of trichogenic potency in cultured postnatal cells. To investigate the feasibility and the limitation of hair regeneration, engineered skin substitutes were prepared with chimeric populations of cultured human kera...

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Veröffentlicht in:	PloS one 2013-06, Vol.8 (6), p.e65664-e65664
Hauptverfasser:	Sriwiriyanont, Penkanok, Lynch, Kaari A, McFarland, Kevin L, Supp, Dorothy M, Boyce, Steven T
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Appendages Biology Cells, Cultured Collagen Dermatology Desaturase Excavation Feasibility studies Fibroblasts Follicles Genetic engineering Glands Growth factors Hair Hair Follicle - growth & development Keratinocytes Medicine Mice Mice, Nude Neonates Real-Time Polymerase Chain Reaction Regeneration Sebaceous glands Sebaceous Glands - physiology Skin Skin, Artificial Stem cells Studies Substitutes Surgery Transgenic mice Water loss Wounds
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