A compendium of nucleosome and transcript profiles reveals determinants of chromatin architecture and transcription

Nucleosomes in all eukaryotes examined to date adopt a characteristic architecture within genes and play fundamental roles in regulating transcription, yet the identity and precise roles of many of the trans-acting factors responsible for the establishment and maintenance of this organization remain...

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Veröffentlicht in:	PLoS genetics 2013-05, Vol.9 (5), p.e1003479-e1003479
Hauptverfasser:	van Bakel, Harm, Tsui, Kyle, Gebbia, Marinella, Mnaimneh, Sanie, Hughes, Timothy R, Nislow, Corey
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine triphosphatase Adenosine Triphosphatases - genetics Architecture Binding sites Biology Chromatin Chromatin Assembly and Disassembly - genetics Chromatin Assembly Factor-1 - genetics Data mining Deoxyribonucleic acid DNA DNA-Binding Proteins - genetics Gene Expression Regulation, Fungal Genes Genetic aspects Genetic transcription Genomes Health aspects Histone Acetyltransferases - genetics Histone Chaperones - genetics Medical research Nucleosomes Physiological aspects Promoter Regions, Genetic Saccharomyces cerevisiae - genetics Saccharomyces cerevisiae Proteins - genetics Trans-Activators - genetics Trans-Activators - metabolism Transcription Factors - genetics Transcription, Genetic Yeast
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