No association of coffee consumption with gastric ulcer, duodenal ulcer, reflux esophagitis, and non-erosive reflux disease: a cross-sectional study of 8,013 healthy subjects in Japan

Probably due to caffeine-induced gastric acid secretion, negative effects of coffee upon various upper-gastrointestinal diseases have been precariously accepted, despite the inadequate epidemiological evidence. Our aim is to evaluate the effect of coffee consumption on four major acid-related diseas...

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Veröffentlicht in:	PloS one 2013-06, Vol.8 (6), p.e65996
Hauptverfasser:	Shimamoto, Takeshi, Yamamichi, Nobutake, Kodashima, Shinya, Takahashi, Yu, Fujishiro, Mitsuhiro, Oka, Masashi, Mitsushima, Toru, Koike, Kazuhiko
Format:	Artikel
Sprache:	eng
Schlagworte:	Acids Adult Adults Age Age Factors Alcohol Alcohol Drinking Alcohol use Alcoholic beverages Analysis Biology Body mass Body Mass Index Body size Caffeine Coffee Coffee - adverse effects Consumption Consumption data Correlation analysis Cross-Sectional Studies Disease Disorders Duodenal ulcer Duodenal Ulcer - epidemiology Duodenal Ulcer - etiology Endoscopes Endoscopy Epidemiology Esophagitis Esophagitis, Peptic - epidemiology Esophagitis, Peptic - etiology Esophagus Family medical history Female Gastroenterology Gastroesophageal reflux Gastrointestinal diseases Gastrointestinal tract diseases Health risk assessment Helicobacter Infections - epidemiology Helicobacter pylori Humans Infections Japan - epidemiology Male Medical research Medicine Medicine, Experimental Meta-analysis Multivariate analysis Pepsinogen A - metabolism Pepsinogen C - metabolism Questionnaires Regression analysis Regurgitation Risk Factors Secretion Sex Factors Smoking Stomach ulcer Stomach Ulcer - epidemiology Stomach Ulcer - etiology Studies Ulcers
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