Changes in circulating procalcitonin versus C-reactive protein in predicting evolution of infectious disease in febrile, critically ill patients

Although absolute values for C-reactive protein (CRP) and procalcitonin (PCT) are well known to predict sepsis in the critically ill, it remains unclear how changes in CRP and PCT compare in predicting evolution of: infectious disease, invasiveness and severity (e.g. development of septic shock, org...

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Veröffentlicht in:	PloS one 2013-06, Vol.8 (6), p.e65564-e65564
Hauptverfasser:	Hoeboer, Sandra H, Groeneveld, A B Johan
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Antibiotics Bacteremia - blood Bacteremia - complications Bacteremia - diagnosis Bacteremia - mortality Biology Biomarkers - blood Body temperature C-reactive protein C-Reactive Protein - metabolism Calcitonin - blood Calcitonin Gene-Related Peptide Communicable diseases Complications Critical Illness - mortality Data acquisition Disease Progression Evolution Failure Female Fever Fever - pathology Health aspects Humans Infection Infections Infectious diseases Intensive care Intensive Care Units Invasiveness Male Medical prognosis Medical research Medicine Microorganisms Middle Aged Mortality Multiple Organ Failure - blood Multiple Organ Failure - diagnosis Multiple Organ Failure - etiology Multiple Organ Failure - mortality Organ Dysfunction Scores Patients Pneumonia Procalcitonin Prognosis Prospective Studies Protein Precursors - blood Proteins Sepsis Sepsis - blood Sepsis - complications Sepsis - diagnosis Sepsis - mortality Septic shock Severity of Illness Index Shock Studies Survival Analysis Ventilators
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