The timing statistics of spontaneous calcium release in cardiac myocytes

A variety of cardiac arrhythmias are initiated by a focal excitation that disrupts the regular beating of the heart. In some cases it is known that these excitations are due to calcium (Ca) release from the sarcoplasmic reticulum (SR) via propagating subcellular Ca waves. However, it is not understo...

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Veröffentlicht in:	PloS one 2013-05, Vol.8 (5), p.e62967-e62967
Hauptverfasser:	Asfaw, Mesfin, Alvarez-Lacalle, Enric, Shiferaw, Yohannes
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Arrhythmia Arrhythmias, Cardiac - metabolism Arrhythmias, Cardiac - physiopathology Biology Calcium Calcium - metabolism Calcium signalling Cardiac muscle Cardiomyocytes Ciències de la salut Computer simulation Excitation Heart Heart diseases Heart rate Humans Mathematical models Medicina Medicine Models, Cardiovascular Myocytes Myocytes, Cardiac - metabolism Parameter identification Physics Physiological aspects Physiological effects Physiological factors Physiology Receptors Receptors (Biologia) Rodents Ryanodine Sarcoplasmic reticulum Sarcoplasmic Reticulum - metabolism Statistical analysis Statistics Studies Time Factors Wave propagation Àrees temàtiques de la UPC
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