Transcriptional profiling of the circulating immune response to lassa virus in an aerosol model of exposure

Lassa virus (LASV) is a significant human pathogen that is endemic to several countries in West Africa. Infection with LASV leads to the development of hemorrhagic fever in a significant number of cases, and it is estimated that thousands die each year from the disease. Little is known about the com...

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Veröffentlicht in:	PLoS neglected tropical diseases 2013-04, Vol.7 (4), p.e2171-e2171
Hauptverfasser:	Malhotra, Shikha, Yen, Judy Y, Honko, Anna N, Garamszegi, Sara, Caballero, Ignacio S, Johnson, Joshua C, Mucker, Eric M, Trefry, John C, Hensley, Lisa E, Connor, John H
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biology Development and progression Drug dosages Fatalities Female Fever Gene expression Gene Expression Profiling - methods Genetic aspects Genetic transcription Genomics Identification and classification Immune system Immunity, Innate - immunology Infections Ir genes Lassa fever Lassa Fever - genetics Lassa Fever - virology Lassa virus - immunology Lassa virus - pathogenicity Leukocytes, Mononuclear - metabolism Macaca - immunology Macaca - virology Male Studies Toll-Like Receptors - metabolism
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