The dorsolateral periaqueductal gray and its role in mediating fear learning to life threatening events

The dorsolateral column of the periaqueductal gray (dlPAG) integrates aversive emotional experiences and represents an important site responding to life threatening situations, such as hypoxia, cardiac pain and predator threats. Previous studies have shown that the dorsal PAG also supports fear lear...

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Veröffentlicht in:	PloS one 2012-11, Vol.7 (11), p.e50361-e50361
Hauptverfasser:	Kincheski, Grasielle C, Mota-Ortiz, Sandra R, Pavesi, Eloisa, Canteras, Newton S, Carobrez, Antônio P
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetic acid Adrenergic receptors Animals Anxiety Aspartate Associative learning Behavior, Animal Biology Brain Brain Mapping - methods Circuits Conditioned stimulus Conditioning Conditioning (Psychology) - physiology Cortex Deactivation Emotions Esters Fear Fear - physiology Fear - psychology Fear conditioning Glutamate receptors Glutamic acid receptors Heart diseases Hippocampus Hypothalamus Hypothalamus - metabolism Hypoxia Inactivation Laboratory animals Learning Male Mediation Medical imaging Memory N-methyl-D-aspartate N-Methyl-D-aspartic acid N-Methylaspartate - chemistry Neurosciences Nuclei Odor Odorants Odors Olfactory pathways Pain Periaqueductal Gray - physiology Periaqueductal gray area Pharmacology Post traumatic stress disorder Rats Rats, Wistar Receptors, N-Methyl-D-Aspartate - chemistry Rodents Sensory stimulation Smell - physiology Social and Behavioral Sciences Studies Thalamus Unconditioned stimulus
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