Within-host evolution of Staphylococcus aureus during asymptomatic carriage

Staphylococcus aureus is a major cause of healthcare associated mortality, but like many important bacterial pathogens, it is a common constituent of the normal human body flora. Around a third of healthy adults are carriers. Recent evidence suggests that evolution of S. aureus during nasal carriage...

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Veröffentlicht in:	PloS one 2013-05, Vol.8 (5), p.e61319
Hauptverfasser:	Golubchik, Tanya, Batty, Elizabeth M, Miller, Ruth R, Farr, Helen, Young, Bernadette C, Larner-Svensson, Hanna, Fung, Rowena, Godwin, Heather, Knox, Kyle, Votintseva, Antonina, Everitt, Richard G, Street, Teresa, Cule, Madeleine, Ip, Camilla L C, Didelot, Xavier, Peto, Timothy E A, Harding, Rosalind M, Wilson, Daniel J, Crook, Derrick W, Bowden, Rory
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Adults Asymptomatic Infections Bacteria Bioinformatics Biology Biomedical research Carrier State Clinical medicine Clostridium difficile Colonization Disease Disease transmission Drug resistance Evolution Evolution, Molecular Fitness Flora Forecasts and trends Gene sequencing Genetics Genome, Bacterial Genomes Health aspects Health care Host-bacteria relationships Humans INDEL Mutation Medical research Medicine Methicillin Mitochondrial DNA Mutation Nose - microbiology Pathogens Phages Plasmids Point mutation Polymorphism, Single Nucleotide Population genetics Proteins Public health Reproductive fitness Selection, Genetic Sequence Analysis, DNA Staphylococcal Infections - microbiology Staphylococcal Infections - transmission Staphylococcus aureus Staphylococcus aureus - genetics Staphylococcus infections
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