Sodium alginate microneedle arrays mediate the transdermal delivery of bovine serum albumin

The "poke and release" strategy for the delivery of macromolecules using polymeric microneedle (MN) is of great importance because it eliminates microneedle reuse, the risks of biohazardous sharps and cross contamination, and it requires no special disposal mechanism. The main objective of...

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Veröffentlicht in:	PloS one 2013-05, Vol.8 (5), p.e63819-e63819
Hauptverfasser:	Demir, Yusuf K, Akan, Zafer, Kerimoglu, Oya
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Cutaneous Albumin Alginates - administration & dosage Alginates - chemistry Alginates - metabolism Alginic acid Analytical methods Antigens Biology Bovine serum albumin Cellulose Conditioning Contamination Diffusion cells Drug delivery Drug Delivery Systems - instrumentation Drug Delivery Systems - methods Drug Stability Engineering Gel electrophoresis Glucuronic Acid - administration & dosage Glucuronic Acid - chemistry Glucuronic Acid - metabolism Hazardous waste management industry Hexuronic Acids - administration & dosage Hexuronic Acids - chemistry Hexuronic Acids - metabolism Humans Hypodermic needles Macromolecules Materials Science Mathematical analysis Mechanical properties Medicine Microinjections - instrumentation Microinjections - methods Needles Patches (structures) Penetration Permeability Pharmaceutical sciences Pharmacy Polymers Polyvinyl alcohol Proteins Rapid prototyping Reproducibility of Results Serum albumin Serum Albumin, Bovine - administration & dosage Serum Albumin, Bovine - chemistry Serum Albumin, Bovine - metabolism Skin Sodium Sodium alginate Sodium dodecyl sulfate Sodium lauryl sulfate Sulfates Surface active agents Transdermal medication Transdermal Patch University faculty
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