Pulmonary Adenocarcinoma in Malignant Pleural Effusion Enriches Cancer Stem Cell Properties during Metastatic Cascade

Metastasis occurs in a series of discrete steps involving invasion, angiogenesis, lymphovascular space permeation, and establishment of secondary tumors. Malignant pleural effusion (MPE), a type of tumor metastasis, is usually a poor prognostic sign for patients with pulmonary adenocarcinoma, althou...

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Veröffentlicht in:	PloS one 2013-05, Vol.8 (5), p.e54659-e54659
Hauptverfasser:	Chen, Su-Feng, Lin, Yaoh-Shiang, Jao, Shu-Wen, Chang, Yun-Ching, Liu, Chia-Lin, Lin, Yu-Ju, Nieh, Shin
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma Adenocarcinoma - metabolism Adenocarcinoma - secondary Aged Aged, 80 and over Analysis Angiogenesis Anoikis Biology Biomarkers Biomarkers, Tumor - metabolism Breast cancer Cancer Care and treatment Cell Proliferation Cell Survival Differentiation E-cadherin Epithelial-Mesenchymal Transition Failure rates Female Humans Identification Immunohistochemistry Invasiveness Ki-67 Antigen - metabolism Life sciences Lung cancer Lung Neoplasms - metabolism Lung Neoplasms - pathology Male Medical prognosis Medicine Mesenchyme Metastases Metastasis Middle Aged Neoplastic Stem Cells - metabolism Oct-4 protein Octamer Transcription Factor-3 - metabolism Pathology Patients Pleural effusion Pleural Effusion, Malignant - metabolism Pleural Effusion, Malignant - pathology Properties (attributes) Risk factors Spheroids, Cellular - metabolism Stem cells Studies Tissues Tumor Cells, Cultured Tumor Microenvironment Tumors Vimentin
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