Cord blood leptin levels of healthy neonates are associated with IFN-γ production by cord blood T-cells

Leptin is a hormone synthesized by adipocytes and other tissues, including the placenta, and it regulates food intake and energy expenditure, reproductive and immune functions. To investigate the role of leptin in neonatal immunity, we measured serum leptin and cytokine (IFN-γ, TNF-α, IL-2, IL-4, IL...

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Veröffentlicht in:	PloS one 2012-07, Vol.7 (7), p.e40830-e40830
Hauptverfasser:	Mouzaki, Athanasia, Panagoulias, Ioannis, Raptis, George, Farri-Kostopoulou, Evagellia
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipocytes Adult Age Analytical methods Angiogenesis Anthropometry Biology Birth Weight Blood Cord blood Cytokines Cytokines - blood Demography Detection limits Diabetes Energy expenditure Female Females Fetal Blood - metabolism Food intake Gender aspects Gender differences Gene expression Gene Expression Regulation Gestational age Health Hematology Humans Immune response Immune system Immunity Immunoglobulins Infant, Newborn Infant, Small for Gestational Age - blood Infants Infections Interferon Interferon-gamma - biosynthesis Interferon-gamma - blood Interleukin 10 Interleukin 12 Interleukin 2 Interleukin 4 Internal medicine Leptin Leptin - blood Lymphocytes Lymphocytes T Male Males Medical prognosis Medicine Metabolism Models, Immunological Monocytes Mothers Neonates Newborn babies Peripheral blood Placenta Rodents Sex differences Small for gestational age T cell receptors T-Lymphocytes - metabolism Tissues Tumor necrosis factor-TNF Tumor necrosis factor-α Womens health γ-Interferon
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