Interferon-beta induces distinct gene expression response patterns in human monocytes versus T cells

Monocytes, which are key players in innate immunity, are outnumbered by neutrophils and lymphocytes among peripheral white blood cells. The cytokine interferon-β (IFN-β) is widely used as an immunomodulatory drug for multiple sclerosis and its functional pathways in peripheral blood mononuclear cell...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	PloS one 2013-04, Vol.8 (4), p.e62366
Hauptverfasser:	Henig, Noa, Avidan, Nili, Mandel, Ilana, Staun-Ram, Elsebeth, Ginzburg, Elizabeta, Paperna, Tamar, Pinter, Ron Y, Miller, Ariel
Format:	Artikel
Sprache:	eng
Schlagworte:	ADP-ribosyl Cyclase 1 - genetics ADP-ribosyl Cyclase 1 - metabolism Antigens Apoptosis Biological response modifiers Biology Biomarkers Blood Blood cells CD83 antigen Cluster Analysis Comparative analysis Computer science Cytokines Dendritic cells Disease Erythrocytes Gene expression Gene Expression Profiling Gene Expression Regulation - drug effects Gene regulation Gene Regulatory Networks Genes Genetic research Genomes Human behavior Humans Immune system Immunity Immunomodulation Infections Inflammation Innate immunity Interferon Interferon-beta - pharmacology Kinases Leukocytes Leukocytes (mononuclear) Leukocytes (neutrophilic) Leukocytes, Mononuclear - drug effects Leukocytes, Mononuclear - metabolism Lymphocytes Lymphocytes T Medicine MicroRNAs Monocytes Monocytes - drug effects Monocytes - metabolism Multiple sclerosis Organ Specificity Pathways Peripheral blood mononuclear cells Polymerase chain reaction Priming Proteins Regulatory sequences Reproducibility of Results Signal Transduction Statistical analysis Statistical analysis of data Studies T cells T-Lymphocytes - drug effects T-Lymphocytes - metabolism Transcription, Genetic Tumor necrosis factor Tumor Necrosis Factor-alpha - pharmacology Tumor necrosis factor-α White blood cells β-Interferon
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!