N-myc downstream regulated gene 1 (NDRG1) promotes metastasis of human scirrhous gastric cancer cells through epithelial mesenchymal transition

Our recent study demonstrated that higher expression of N-myc downregulated gene 1 (NDRG1) is closely correlated with poor prognosis in gastric cancer patients. In this study, we asked whether NDRG1 has pivotal roles in malignant progression including metastasis of gastric cancer cells. By gene expr...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	PloS one 2012-07, Vol.7 (7), p.e41312-e41312
Hauptverfasser:	Ureshino, Hiroki, Murakami, Yuichi, Watari, Kosuke, Izumi, Hiroto, Kawahara, Akihiko, Kage, Masayoshi, Arao, Tokuzo, Nishio, Kazuto, Yanagihara, Kazuyoshi, Kinoshita, Hisafumi, Kuwano, Michihiko, Ono, Mayumi
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma, Scirrhous - genetics Adenocarcinoma, Scirrhous - metabolism Adenocarcinoma, Scirrhous - pathology Analysis Angiogenesis Animal tissues Animals Ascites Biology Biotechnology Breast cancer Cadherins - genetics Cancer Cancer cells Cancer genetics Cancer metastasis Cell adhesion & migration Cell Cycle Proteins - deficiency Cell Cycle Proteins - genetics Cell Cycle Proteins - metabolism Cell growth Cell Line, Tumor Cell Proliferation Colorectal cancer Development and progression DNA microarrays Down-Regulation E-cadherin Epithelial-Mesenchymal Transition Female Gastric cancer Gene expression Gene Knockdown Techniques Genes Genetic aspects Genomes Growth factors Humans Intermediate filament proteins Intracellular Signaling Peptides and Proteins - deficiency Intracellular Signaling Peptides and Proteins - genetics Intracellular Signaling Peptides and Proteins - metabolism Kidney cancer Kinases Lung cancer Medical prognosis Medicine Mesenchyme Metastases Metastasis Mice Morphology Myc protein Neoplasm Metastasis Oncology Peritoneum Peritoneum - metabolism Peritoneum - pathology Pharmaceutical sciences Prognosis Promoter Regions, Genetic - genetics Prostate cancer Stem cells Stomach cancer Stomach Neoplasms - genetics Stomach Neoplasms - metabolism Stomach Neoplasms - pathology Studies Survival Transcription Factors - metabolism Transcriptome Up-Regulation Vimentin Vimentin - metabolism Wound healing
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!