A dual-color luciferase assay system reveals circadian resetting of cultured fibroblasts by co-cultured adrenal glands

In mammals, circadian rhythms of various organs and tissues are synchronized by pacemaker neurons in the suprachiasmatic nucleus (SCN) of the hypothalamus. Glucocorticoids released from the adrenal glands can synchronize circadian rhythms in other tissues. Many hormones show circadian rhythms in the...

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Veröffentlicht in:	PloS one 2012-05, Vol.7 (5), p.e37093-e37093
Hauptverfasser:	Noguchi, Takako, Ikeda, Masaaki, Ohmiya, Yoshihiro, Nakajima, Yoshihiro
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenal glands Adrenal Glands - cytology Adrenal Glands - metabolism Adrenal Glands - physiology Animal tissues Animals Biology Brain research Cell Communication - physiology Cell culture Cell interactions Circadian rhythm Circadian Rhythm - genetics Circadian Rhythm - physiology Circadian rhythms Clock gene Coculture Techniques - methods Color Communications systems Cortical Synchronization - genetics Cortical Synchronization - physiology Fibroblasts Fibroblasts - cytology Fibroblasts - metabolism Fibroblasts - physiology Gene expression Genes Genetic engineering Glucocorticoids Homeostasis Hormones Hostages Hypothalamus Luciferase Luciferases - analysis Luciferases - metabolism Lungs Medical research Medicine Melatonin Mice Mice, Inbred C57BL Mice, Transgenic Organs Period Circadian Proteins - genetics Period Circadian Proteins - metabolism Promoter Regions, Genetic Rodents Signal Transduction Suprachiasmatic nucleus Suprachiasmatic Nucleus - metabolism Suprachiasmatic Nucleus - physiology Synchronism Synchronizers Thyroid Thyroid gland Tissues Tracking Transgenic mice
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