Role of alveolar β2-adrenergic receptors on lung fluid clearance and exercise ventilation in healthy humans

In experimental conditions alveolar fluid clearance is controlled by alveolar β2-adrenergic receptors. We hypothesized that if this occurs in humans, then non-selective β-blockers should reduce the membrane diffusing capacity (DM), an index of lung interstitial fluid homeostasis. Moreover, we wonder...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	PloS one 2013-04, Vol.8 (4), p.e61877
Hauptverfasser:	Paolillo, Stefania, Pellegrino, Riccardo, Salvioni, Elisabetta, Contini, Mauro, Iorio, Annamaria, Bovis, Francesca, Antonelli, Andrea, Torchio, Roberto, Gulotta, Carlo, Locatelli, Alessandro, Agostoni, Piergiuseppe
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenergic receptors Adult Alveoli Biology Bisoprolol - therapeutic use Carbazoles - therapeutic use Carbon dioxide Carbon monoxide Diffusion barriers Edema Exercise - physiology Extracellular Fluid - metabolism Heart failure Heart rate Homeostasis Humans Hyperventilation Hyperventilation - metabolism Hypotheses In vivo methods and tests Infusion Lung - drug effects Lung - metabolism Lungs Male Males Medicine Physical training Propanolamines - therapeutic use Pulmonary Diffusing Capacity - drug effects Receptors Receptors (physiology) Receptors, Adrenergic, beta-2 - genetics Receptors, Adrenergic, beta-2 - metabolism Respiratory Function Tests Saline solutions Slopes Ventilation Ventilators Young Adult
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!