Influenza nucleoprotein delivered with aluminium salts protects mice from an influenza A virus that expresses an altered nucleoprotein sequence

Influenza virus poses a difficult challenge for protective immunity. This virus is adept at altering its surface proteins, the proteins that are the targets of neutralizing antibody. Consequently, each year a new vaccine must be developed to combat the current recirculating strains. A universal infl...

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Veröffentlicht in:PloS one 2013-04, Vol.8 (4), p.e61775-e61775
Hauptverfasser: Macleod, Megan K L, David, Alexandria, Jin, Niyun, Noges, Laura, Wang, Jieru, Kappler, John W, Marrack, Philippa
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Sprache:eng
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