Decreased FOXF2 mRNA expression indicates early-onset metastasis and poor prognosis for breast cancer patients with histological grade II tumor

The transcription factor, FOXF2, plays an important role in tissue development, extracellular matrix synthesis, and epithelial-mesenchymal interactions, implying that it may be associated with the metastatic capabilities of cancer cells. However, the relationship between FOXF2 expression and breast...

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Veröffentlicht in:	PloS one 2013-04, Vol.8 (4), p.e61591-e61591
Hauptverfasser:	Kong, Peng-Zhou, Yang, Fan, Li, Lin, Li, Xiao-Qing, Feng, Yu-Mei
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Age Biochemistry Breast cancer Breast Neoplasms - genetics Breast Neoplasms - pathology Cancer Cancer metastasis Cancer patients Cancer research Cancer therapies Cell cycle Development and progression Disease prevention Disease-Free Survival Endocrine therapy Extracellular matrix Female Forkhead Transcription Factors - genetics Forkhead Transcription Factors - metabolism Gene expression Gene Expression Regulation, Neoplastic Humans Kaplan-Meier Estimate Laboratories Lymph nodes Lymphatic Metastasis - genetics Lymphatic Metastasis - pathology Medical prognosis Medicine Mesenchyme Messenger RNA Metastases Metastasis Middle Aged Molecular biology Multivariate Analysis Neoplasm Grading Patients Prognosis Prostate Reproducibility of Results RNA, Messenger - genetics RNA, Messenger - metabolism Rodents Stem cells Studies Time Factors Tissues Transcription factors Tumors
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