Reproducibility of non-invasive assessment of skin endothelial function using laser Doppler flowmetry and laser speckle contrast imaging

Endothelial dysfunction precedes atherosclerosis. Vasodilation induced by acetylcholine (ACh) is a specific test of endothelial function. Reproducibility of laser techniques such as laser-Doppler-flowmetry (LDF) and Laser-speckle-contrast-imaging (LSCI) to detect ACh vasodilation is debated and resu...

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Veröffentlicht in:	PloS one 2013-04, Vol.8 (4), p.e61320-e61320
Hauptverfasser:	Puissant, Cyril, Abraham, Pierre, Durand, Sylvain, Humeau-Heurtier, Anne, Faure, Sébastien, Lefthériotis, Georges, Rousseau, Pascal, Mahé, Guillaume
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetylcholine Acetylcholine - administration & dosage Acetylcholine - pharmacology Adult Arteriosclerosis Atherosclerosis Biology Coefficient of variation Conductance Contrast Media Correlation coefficient Correlation coefficients Diagnostic Imaging - methods Doppler effect Endothelium Endothelium, Vascular - drug effects Endothelium, Vascular - physiology Female Hospitals Humans Iontophoresis Laboratories Laser-Doppler Flowmetry - methods Lasers Life Sciences Male Medicine Reproducibility Reproducibility of Results Resistance Skin Skin - blood supply Skin - drug effects Standardization Vasodilation Vasodilation - drug effects
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