Effects of two commonly found strains of influenza A virus on developing dopaminergic neurons, in relation to the pathophysiology of schizophrenia

Influenza virus (InfV) infection during pregnancy is a known risk factor for neurodevelopment abnormalities in the offspring, including the risk of schizophrenia, and has been shown to result in an abnormal behavioral phenotype in mice. However, previous reports have concentrated on neuroadapted inf...

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Veröffentlicht in:	PloS one 2012-12, Vol.7 (12), p.e51068-e51068
Hauptverfasser:	Landreau, Fernando, Galeano, Pablo, Caltana, Laura R, Masciotra, Luis, Chertcoff, Agustín, Pontoriero, A, Baumeister, Elsa, Amoroso, Marcela, Brusco, Herminia A, Tous, Mónica I, Savy, Vilma L, Lores Arnaiz, María del Rosario, de Erausquin, Gabriel A
Format:	Artikel
Sprache:	eng
Schlagworte:	Abnormalities Animals Antigens Apoptosis Behavior, Animal - physiology Biology Brain Brain - immunology Brain - physiopathology Brain - virology Cells, Cultured Development and progression Disease Models, Animal Dopamine Dopamine receptors Dopaminergic Neurons - virology Female Gene expression Health aspects House mouse Infections Influenza Influenza A Influenza A Virus, H1N1 Subtype Influenza A Virus, H3N2 Subtype Influenza viruses Kinases Maze Learning - physiology Medicine Mental disorders Mice Neurodevelopmental disorders Neurons Offspring Orthomyxoviridae Infections - immunology Orthomyxoviridae Infections - physiopathology Orthomyxoviridae Infections - virology Pregnancy Pregnant women Prenatal Exposure Delayed Effects - immunology Prenatal Exposure Delayed Effects - physiopathology Prenatal Exposure Delayed Effects - virology Recognition, Psychology - physiology Risk factors Rodents Schizophrenia Schizophrenia - virology Signal transduction Strains (organisms) Viruses
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