Programmable in vivo selection of arbitrary DNA sequences

The extraordinary fidelity, sensory and regulatory capacity of natural intracellular machinery is generally confined to their endogenous environment. Nevertheless, synthetic bio-molecular components have been engineered to interface with the cellular transcription, splicing and translation machinery...

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Veröffentlicht in:	PloS one 2012-11, Vol.7 (11), p.e47795-e47795
Hauptverfasser:	Ben Yehezkel, Tuval, Biezuner, Tamir, Linshiz, Gregory, Mazor, Yair, Shapiro, Ehud
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis Applied mathematics Bacteria Base Sequence Binding sites Biology Computer science Deoxyribonucleic acid Devices DNA DNA - chemistry DNA methylation DNA repair DNA sequencing E coli Embedding Engineering Environmental engineering Escherichia coli Gene expression Gene Library Gene sequencing Intracellular Introns Mismatch repair Mutation Nucleotide sequence Software Splicing Synthetic biology Transcription
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