IL12RB2 gene is associated with the age of type 1 diabetes onset in Croatian family Trios

Common complex diseases are influenced by both genetic and environmental factors. Many genetic factors overlap between various autoimmune diseases. The aim of the present study is to determine whether four genetic variants known to be risk variants for several autoimmune diseases could be associated...

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Veröffentlicht in:	PloS one 2012-11, Vol.7 (11), p.e49133-e49133
Hauptverfasser:	Pehlić, Marina, Vrkić, Dina, Skrabić, Veselin, Jerončić, Ana, Stipančić, Gordana, Urojić, Anita Špehar, Marjanac, Igor, Jakšić, Jasminka, Kačić, Zrinka, Boraska, Vesna, Zemunik, Tatijana
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Age of Onset Alleles Annexins - genetics ANXA11 gene Arthritis Autoimmune diseases Biology Celiac disease Child Cirrhosis Croatia - epidemiology Cytokines Cytoskeletal Proteins - genetics Diabetes Diabetes mellitus Diabetes Mellitus, Type 1 - epidemiology Diabetes Mellitus, Type 1 - genetics Disease Diseases Environmental factors Epidemiology Families & family life Family Female Gene polymorphism Genes Genetic aspects Genetic Association Studies Genetic diversity Genetic factors Genetic polymorphisms Genetic Predisposition to Disease Genetic variance Genomes Health risks Hospitals Humans IL12Rb2 protein Interleukin 1 LIM Domain Proteins - genetics Linkage Disequilibrium - genetics Liver cirrhosis Male Medical research Medicine Pediatrics Permutations Polymorphism Polymorphism, Single Nucleotide - genetics Primary biliary cirrhosis Proteins Receptors, Interleukin-12 - genetics Rheumatoid arthritis Risk factors Sarcoidosis Studies V-Set Domain-Containing T-Cell Activation Inhibitor 1 - genetics
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