Intentional weight loss and dose reductions of anti-diabetic medications--a retrospective cohort study

Intentional weight loss, primarily by improving insulin resistance, is known to decrease the need for anti-diabetic medications. In this study, we assess the magnitude of weight loss that resulted in dose reductions or discontinuation of anti-diabetic medications in overweight or obese patients with...

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Veröffentlicht in:	PloS one 2012-02, Vol.7 (2), p.e32395-e32395
Hauptverfasser:	Kumar, Anita Ashok, Palamaner Subash Shantha, Ghanshyam, Kahan, Scott, Samson, Rohit Joshua, Boddu, Nelson David, Cheskin, Lawrence Jay
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Analysis Antidiabetics Antihypertensive agents Biology Blood glucose Body mass Body Mass Index Body weight Body weight loss Cardiovascular disease Clinical trials Cohort analysis Cohort Studies Decision analysis Diabetes Complications - therapy Diabetes mellitus Diabetes mellitus (non-insulin dependent) Diabetes Mellitus, Type 2 - drug therapy Diabetes Mellitus, Type 2 - therapy Diabetes therapy Drugs Female Health risk assessment Humans Hypoglycemic Agents - pharmacology Insulin Insulin - pharmacology Insulin resistance Male Medicine Metformin Middle Aged Obesity Obesity - complications Overweight Overweight - complications Patients Pyrazines - pharmacology Regression Analysis Retrospective Studies Sitagliptin Phosphate Sugar Sulfonylurea Compounds - pharmacology Triazoles - pharmacology Type 2 diabetes Weight loss Weight Loss - drug effects Weight reduction
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