Morphology and nanomechanics of sensory neurons growth cones following peripheral nerve injury

A prior peripheral nerve injury in vivo, promotes a rapid elongated mode of sensory neurons neurite regrowth in vitro. This in vitro model of conditioned axotomy allows analysis of the cellular and molecular mechanisms leading to an improved neurite re-growth. Our differential interference contrast...

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Veröffentlicht in:	PloS one 2013-02, Vol.8 (2), p.e56286-e56286
Hauptverfasser:	Martin, Marta, Benzina, Ouafa, Szabo, Vivien, Végh, Attila-Gergely, Lucas, Olivier, Cloitre, Thierry, Scamps, Frédérique, Gergely, Csilla
Format:	Artikel
Sprache:	eng
Schlagworte:	Actins - metabolism Animals Atomic force microscopy Axonogenesis Axotomy Axotomy - methods Biological Physics Biology Biomechanical Phenomena Cells, Cultured Chemistry Conditioning Cones Dorsal root ganglia Elasticity Elongation Female Ganglia Ganglia, Spinal - cytology Ganglia, Spinal - metabolism Ganglia, Spinal - physiology Growth Growth cones Growth Cones - metabolism Growth Cones - physiology Immunocytochemistry Immunohistochemistry Injuries Materials Science Mechanical properties Membrane elasticity Mice Microscopes Microscopy Microscopy, Atomic Force Microscopy, Phase-Contrast Molecular modelling Morphology Nerve Regeneration - physiology Neurons Peripheral Nerve Injuries - physiopathology Physics Proteins Regrowth Sciatic nerve Sciatic Nerve - injuries Sensory neurons Sensory Receptor Cells - metabolism Sensory Receptor Cells - physiology Structural proteins Studies Three dimensional imaging Tubulin - metabolism
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