Cost-effectiveness of Quantiferon®-TB Gold-in-Tube versus tuberculin skin testing for contact screening and treatment of latent tuberculosis infection in Brazil

Latent tuberculosis infection (LTBI) is a reservoir for new TB cases. Isoniazid preventive therapy (IPT) reduces the risk of active TB by as much as 90%, but LTBI screening has limitations. Unlike tuberculin skin testing (TST), interferon-gamma release assays are not affected by BCG vaccination, and...

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Veröffentlicht in:	PloS one 2013-04, Vol.8 (4), p.e59546-e59546
Hauptverfasser:	Steffen, Ricardo Ewbank, Caetano, Rosângela, Pinto, Márcia, Chaves, Diogo, Ferrari, Rossini, Bastos, Mayara, de Abreu, Sandra Teixeira, Menzies, Dick, Trajman, Anete
Format:	Artikel
Sprache:	eng
Schlagworte:	Adults Analysis Bacillus Calmette-Guerin vaccine BCG Brazil Care and treatment Contact Tracing - economics Contact Tracing - methods Cost analysis Cost-Benefit Analysis Costs Decision Trees Diagnosis Disease prevention Economic aspects Health aspects Health education Health surveillance HIV Human immunodeficiency virus Humans Immunization Infections Interferon Interferon-gamma Release Tests - economics Isoniazid Latent Tuberculosis - diagnosis Latent Tuberculosis - drug therapy Latent Tuberculosis - economics Mass Screening - economics Medical diagnosis Medicine Models, Econometric Public health Screening Skin tests Systematic review Tuberculin Tuberculin test Tuberculin Test - economics Tuberculosis Ultrasonic testing Vaccination
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