DNA methylation profiles at precancerous stages associated with recurrence of lung adenocarcinoma

The aim of this study was to clarify the significance of DNA methylation alterations at precancerous stages of lung adenocarcinoma. Using single-CpG resolution Infinium array, genome-wide DNA methylation analysis was performed in 36 samples of normal lung tissue obtained from patients without any pr...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	PloS one 2013-03, Vol.8 (3), p.e59444
Hauptverfasser:	Sato, Takashi, Arai, Eri, Kohno, Takashi, Tsuta, Koji, Watanabe, Shun-ichi, Soejima, Kenzo, Betsuyaku, Tomoko, Kanai, Yae
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma Adenocarcinoma - genetics Adenocarcinoma - pathology Adenocarcinoma of Lung Adult Aged Aged, 80 and over Apoptosis Azacitidine - pharmacology Biology Cell adhesion CpG islands Deoxyribonucleic acid DNA DNA methylation DNA Methylation - drug effects DNA Methylation - genetics DNA Probes - metabolism Epigenetics Female Gene expression Gene Expression Regulation, Neoplastic - drug effects Gene regulation Gene Silencing Genes Genes, Neoplasm - genetics Genomes Humans Leukemia Lung cancer Lung diseases Lung Neoplasms - genetics Lung Neoplasms - pathology Male Medical imaging Medicine Middle Aged Mutation Neoplasm Recurrence, Local - genetics Neoplasm Recurrence, Local - pathology Neoplasm Staging Pathology Patients Precancerous Conditions - genetics Precancerous Conditions - pathology Proportional Hazards Models RNA, Messenger - genetics RNA, Messenger - metabolism Thoracic surgery Transcription Tumor cell lines Tumors
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!