Ultrasound-guided intramural inoculation of orthotopic bladder cancer xenografts: a novel high-precision approach

Orthotopic bladder cancer xenografts are essential for testing novel therapies and molecular manipulations of cell lines in vivo. Current xenografts rely on tumor cell inoculation by intravesical instillation or direct injection into the bladder wall. Instillation is limited by the lack of cell line...

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Veröffentlicht in:	PloS one 2013-03, Vol.8 (3), p.e59536-e59536
Hauptverfasser:	Jäger, Wolfgang, Moskalev, Igor, Janssen, Claudia, Hayashi, Tetsutaro, Awrey, Shannon, Gust, Kilian M, So, Alan I, Zhang, Kaixin, Fazli, Ladan, Li, Estelle, Thüroff, Joachim W, Lange, Dirk, Black, Peter C
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenoviruses Angiogenesis Animals Biology Bioluminescence Biotechnology Bladder Bladder cancer Cancer Cell Line, Tumor Cell Proliferation Chemical compounds Chemotherapy Cisplatin Complications Feasibility Studies Female Gemcitabine Gene therapy Humans Immunohistochemistry In vivo methods and tests Injection Inoculation Medicine Mice Morbidity Mucosa Muscles NMR Nuclear magnetic resonance Oncolysis Oncolytic Viruses - physiology Perfusion Pharmacology Prostate Surgery, Computer-Assisted - methods Transplantation, Heterologous - methods Tumor cell lines Tumor cells Tumors Ultrasonic imaging Ultrasonics Ultrasound Urinary bladder Urinary Bladder Neoplasms - drug therapy Urinary Bladder Neoplasms - pathology Urinary Bladder Neoplasms - virology Urology Vascular endothelial growth factor Viruses Xenografts Xenotransplantation
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