CD24 induces expression of the oncomir miR-21 via Src, and CD24 and Src are both post-transcriptionally downregulated by the tumor suppressor miR-34a

Cancer is a complex disease process that evolves as a consequence of multiple malfunctions in key regulatory molecular networks. Understanding these networks will be essential to combat cancer. In this study, we focussed on central players in such networks. In a series of colon and breast cancer cel...

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Veröffentlicht in:PloS one 2013-03, Vol.8 (3), p.e59563-e59563
Hauptverfasser: Muppala, Santoshi, Mudduluru, Giridhar, Leupold, Jörg H, Buergy, Daniel, Sleeman, Jonathan P, Allgayer, Heike
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Sprache:eng
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