Whole genome gene expression meta-analysis of inflammatory bowel disease colon mucosa demonstrates lack of major differences between Crohn's disease and ulcerative colitis

In inflammatory bowel disease (IBD), genetic susceptibility together with environmental factors disturbs gut homeostasis producing chronic inflammation. The two main IBD subtypes are Ulcerative colitis (UC) and Crohn's disease (CD). We present the to-date largest microarray gene expression stud...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	PloS one 2013-02, Vol.8 (2), p.e56818-e56818
Hauptverfasser:	Granlund, Atle van Beelen, Flatberg, Arnar, Østvik, Ann E, Drozdov, Ignat, Gustafsson, Bjørn I, Kidd, Mark, Beisvag, Vidar, Torp, Sverre H, Waldum, Helge L, Martinsen, Tom Christian, Damås, Jan Kristian, Espevik, Terje, Sandvik, Arne K
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Analysis Antimicrobial Cationic Peptides - genetics Archives & records Biology Cancer Cell adhesion & migration Cell differentiation Cluster Analysis Colitis Colitis, Ulcerative - genetics Colitis, Ulcerative - immunology Colon Colon - immunology Colon - metabolism Crohn Disease - genetics Crohn Disease - immunology Crohn's disease Crohns disease Cytokines Data processing Differentiation (biology) Disease susceptibility DNA microarrays Environmental factors Female Gastroenterology Gastrointestinal diseases Gene expression Gene Expression Profiling Gene Expression Regulation Genes Genetic aspects Genome, Human Genomes Genomics Helper cells Hepatology Homeostasis Hospitals Humans Inflammation Inflammatory bowel disease Inflammatory bowel diseases Inflammatory Bowel Diseases - genetics Inflammatory Bowel Diseases - immunology Intestinal Mucosa - immunology Intestinal Mucosa - metabolism Intestine Lymphocytes T Male Mathematical models Medical research Medicine Meta-analysis Middle Aged Molecular biology Mucosa Patients Proteins Science Statistical methods Studies T-Lymphocytes, Helper-Inducer - immunology T-Lymphocytes, Helper-Inducer - metabolism Ulcerative colitis Young Adult
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!