γ-Tocotrienol induces paraptosis-like cell death in human colon carcinoma SW620 cells

Colorectal cancer is one of the most serious illnesses among diagnosed cancer. As a new type of anti-cancer composition from tocotrienol-rich fraction of palm oil, γ-tocotrienol is widely used in anti-cancer research. The objectives of this study were to investigate the effects of γ-tocotrienol on h...

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Veröffentlicht in:	PloS one 2013-02, Vol.8 (2), p.e57779
Hauptverfasser:	Zhang, Jing-Shu, Li, Da-Ming, Ma, Yue, He, Ning, Gu, Qing, Wang, Feng-Shan, Jiang, Shu-Qing, Chen, Bing-Qing, Liu, Jia-Ren
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic Agents - pharmacology Apoptosis Biology Breast cancer c-Jun protein Cancer Caspase 3 - metabolism Cell cycle Cell death Cell Death - drug effects Cell Line, Tumor Cell Proliferation - drug effects Chromans - pharmacology Colon Colon cancer Colonic Neoplasms - pathology Colorectal cancer Colorectal carcinoma Cyclin D1 Disease control Disease prevention Endoplasmic reticulum Enzyme Activation - drug effects Gene Expression Regulation, Neoplastic - drug effects Humans Illnesses Kinases Medicine Mens health Mortality Natural products Palm oil Polymerase chain reaction Proteins Public health Rodents Signal transduction Signal Transduction - drug effects Signaling Stem cells Toxicology Transcription factors Vacuoles - drug effects Vacuoles - metabolism Vitamin E - analogs & derivatives Vitamin E - pharmacology Wnt protein Wnt Proteins - genetics Wnt Proteins - metabolism Womens health β-Catenin
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