Identification and characterization of microRNAs controlled by the osteoblast-specific transcription factor Osterix

Osterix (Osx) is an osteoblast-specific transcription factor which is essential for bone formation. MicroRNAs (miRNAs) have been previously shown to be involved in osteogenesis. However, it is unclear whether Osx is involved in the regulation of miRNA expression. In this study, we have identified gr...

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Veröffentlicht in:	PloS one 2013-03, Vol.8 (3), p.e58104-e58104
Hauptverfasser:	Chen, Qin, Liu, Wenbin, Sinha, Krishna M, Yasuda, Hideyo, de Crombrugghe, Benoit
Format:	Artikel
Sprache:	eng
Schlagworte:	Adaptor Proteins, Signal Transducing Alkaline phosphatase Alkaline Phosphatase - metabolism Animals Biocompatibility Bioinformatics Biology Bone growth Bones Calvaria Cancer Cbfa-1 protein Cell cycle Comparative analysis Control Correlation Correlation analysis Embryos Gene expression Gene Expression Regulation, Developmental Genotype Glycoproteins - metabolism Intercellular Signaling Peptides and Proteins Mice Mice, Knockout MicroRNA MicroRNAs MicroRNAs - metabolism miRNA Molecular modelling Osteoblastogenesis Osteogenesis Osteogenesis - genetics Overexpression Proteins Signal Transduction Signaling Skull - metabolism SOST protein Sp7 Transcription Factor Time Factors Transcription factors Transcription Factors - genetics Transcription Factors - physiology Wnt protein
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