Common genetic variants in Wnt signaling pathway genes as potential prognostic biomarkers for colorectal cancer

Compelling evidence has implicated the Wnt signaling pathway in the pathogenesis of colorectal cancer. We assessed the use of tag single nucleotide polymorphisms (tSNPs) in adenomatous polyposis coli (APC)/β-catenin (CTNNB1) genes to predict outcomes in patients with colorectal cancer. We selected a...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	PloS one 2013-02, Vol.8 (2), p.e56196-e56196
Hauptverfasser:	Ting, Wen-Chien, Chen, Lu-Min, Pao, Jiunn-Bey, Yang, Ying-Pi, You, Bang-Jau, Chang, Ta-Yuan, Lan, Yu-Hsuan, Lee, Hong-Zin, Bao, Bo-Ying
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenomatous polyposis coli Adenomatous polyposis coli protein Adenomatous Polyposis Coli Protein - genetics Aged Analysis Antigen-presenting cells Antigens beta Catenin - genetics Bioindicators Bioinformatics Biomarkers Biomarkers, Tumor - genetics Cancer Cancer genetics Cancer metastasis Carcinoembryonic antigen Clinical outcomes Colorectal cancer Colorectal carcinoma Colorectal Neoplasms - genetics Colorectal Neoplasms - mortality Colorectal Neoplasms - pathology Colorectal surgery Development and progression DNA, Neoplasm - genetics Female Follow-Up Studies Gene expression Genes Genetic aspects Genetic diversity Genetic variance Haplotypes Hospitals Humans Kinases Lymph nodes Male Medical prognosis Medical research Medicine Metastases Metastasis Middle Aged Neoplasm Invasiveness Neoplasm Staging Pathogenesis Patients Pharmacy Polymerase Chain Reaction Polymorphism, Single Nucleotide - genetics Polyposis coli Prognosis Prostate Regression analysis Regression models Signal transduction Signaling Single nucleotide polymorphisms Single-nucleotide polymorphism Survival Survival Rate Wnt protein Wnt Signaling Pathway β-Catenin
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!