Ischemic preconditioning increases endothelial progenitor cell number to attenuate partial nephrectomy-induced ischemia/reperfusion injury

The objective of this study was to investigate the role of endothelial progenitor cells (EPCs) in the modulation of ischemia-reperfusion injury (IRI) in a partial nephrectomy (PN) rat model using early-phase ischemic preconditioning (IPC). Ninety male Sprague-Dawley rats were randomly divided into t...

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Veröffentlicht in:	PloS one 2013-01, Vol.8 (1), p.e55389-e55389
Hauptverfasser:	Liu, Hao, Wu, Ran, Jia, Rui-Peng, Zhong, Bing, Zhu, Jia-Geng, Yu, Peng, Zhao, Yan, Ge, Yu-Zheng, Wu, Jian-Ping
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis of Variance Angiogenesis Animals Biology Blood vessels Blotting, Western Bone marrow Capillaries Cell number Cell proliferation Cells (biology) Chemokine CXCL12 - metabolism Clamping DNA Primers - genetics Endothelial Cells - physiology Endothelium Epithelial cells Flow Cytometry Fluorescent Antibody Technique Histological Techniques Hospitals Immunohistochemistry Injuries Ischemia Ischemic Preconditioning - methods Kidneys Male Medicine Neovascularization, Physiologic - physiology Nephrectomy Nephrectomy - adverse effects Polymerase Chain Reaction Preconditioning Progenitor cells Rats Rats, Sprague-Dawley Renal function Reperfusion Reperfusion Injury - etiology Reperfusion Injury - prevention & control Rodents Stem cells Stem Cells - physiology Studies Surgery Urology Vascular endothelial growth factor Vascular Endothelial Growth Factor A - metabolism Veins & arteries
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