Regulation of two renal chloride transporters, AE1 and pendrin, by electrolytes and aldosterone

The renal handling of salt and protons and bicarbonate are intricately linked through shared transport mechanisms for sodium, chloride, protons, and bicarbonate. In the collecting duct, the regulated fine-tuning of salt and acid-base homeostasis is achieved by a series of transport proteins located...

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Veröffentlicht in:	PloS one 2013-01, Vol.8 (1), p.e55286
Hauptverfasser:	Mohebbi, Nilufar, Perna, Angelica, van der Wijst, Jenny, Becker, Helen M, Capasso, Giovambattista, Wagner, Carsten A
Format:	Artikel
Sprache:	eng
Schlagworte:	Abundance Acidosis Acids Adenosine triphosphatase Aldosterone Aldosterone - metabolism Ammonium Chloride - pharmacology Analysis of Variance Animals Anion Exchange Protein 1, Erythrocyte - metabolism Anion exchanging Anion Transport Proteins - metabolism Bicarbonates Bicarbonates - pharmacology Biology Blood pressure Blotting, Western Carbonates Chloride Chloride transport Chromatography, Ion Exchange Collecting duct Desoxycorticosterone Diet Dietary intake Drinking water Electrolytes Electrolytes - metabolism Electrolytes - urine Electrolytic cells Gene expression Gene Expression Regulation - drug effects Glucocorticoids Homeostasis Hydrogen-Ion Concentration Hypertension Immunohistochemistry Internal medicine Kidney Tubules, Collecting - metabolism Kidneys Laboratory animals Male Mathematics Medicine Metabolism Mice Mice, Inbred C57BL mRNA Nephrology Physiology Potassium chloride Potassium Compounds - pharmacology Proteins Protons Reabsorption Real-Time Polymerase Chain Reaction Renal cortex Renal function Reverse Transcriptase Polymerase Chain Reaction RNA Rodents Salts Sodium Sodium Bicarbonate - pharmacology Sodium chloride Steroids (Organic compounds) Transport Urine
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