Comprehensive analysis of DNA methylation in head and neck squamous cell carcinoma indicates differences by survival and clinicopathologic characteristics

Head and neck squamous cell carcinoma (HNSCC) is the eighth most commonly diagnosed cancer in the United States. The risk of developing HNSCC increases with exposure to tobacco, alcohol and infection with human papilloma virus (HPV). HPV-associated HNSCCs have a distinct risk profile and improved pr...

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Veröffentlicht in:	PloS one 2013-01, Vol.8 (1), p.e54742
Hauptverfasser:	Colacino, Justin A, Dolinoy, Dana C, Duffy, Sonia A, Sartor, Maureen A, Chepeha, Douglas B, Bradford, Carol R, McHugh, Jonathan B, Patel, Divya A, Virani, Shama, Walline, Heather M, Bellile, Emily, Terrell, Jeffrey E, Stoerker, Jay A, Taylor, Jeremy M G, Carey, Thomas E, Wolf, Gregory T, Rozek, Laura S
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Alcohol use Alcoholic beverages Base Sequence Biology Biomarkers Cancer Carcinogenesis Carcinogens Carcinoma, Squamous Cell - genetics Carcinoma, Squamous Cell - pathology Carcinoma, Squamous Cell - virology Care and treatment Cell cycle Cell survival Cluster Analysis Clustering CpG Islands Deoxyribonucleic acid Development and progression DNA DNA Methylation DNA Primers Environmental health Epidemiology Epigenetics Exposure Female Gene expression Genes Genetic aspects Genomics Genotypes Head Head & neck cancer Head and neck cancer Head and Neck Neoplasms - genetics Head and Neck Neoplasms - pathology Head and Neck Neoplasms - virology Health aspects Health risks Health sciences Human papillomavirus Humans Hybridization Male Medical research Medical schools Medicine Middle Aged Mutation Otolaryngology Patients Polymerase Chain Reaction Public health Risk assessment Smoking Squamous cell carcinoma Survival Survival Analysis Tobacco Tumors Viruses Young Adult
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