Method for quantitative study of airway functional microanatomy using micro-optical coherence tomography

We demonstrate the use of a high resolution form of optical coherence tomography, termed micro-OCT (μOCT), for investigating the functional microanatomy of airway epithelia. μOCT captures several key parameters governing the function of the airway surface (airway surface liquid depth, periciliary li...

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Veröffentlicht in:	PloS one 2013-01, Vol.8 (1), p.e54473-e54473
Hauptverfasser:	Liu, Linbo, Chu, Kengyeh K, Houser, Grace H, Diephuis, Bradford J, Li, Yao, Wilsterman, Eric J, Shastry, Suresh, Dierksen, Gregory, Birket, Susan E, Mazur, Marina, Byan-Parker, Suzanne, Grizzle, William E, Sorscher, Eric J, Rowe, Steven M, Tearney, Guillermo J
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biology Bronchi - physiology Bronchi - ultrastructure Chronic obstructive pulmonary disease Cilia - physiology Cilia - ultrastructure Coherence Cystic fibrosis Dermatology Engineering Epithelial cells Epithelial Cells - physiology Epithelial Cells - ultrastructure Extrusion Glands Health sciences High resolution Hospitals Humans Medical imaging Medical schools Medicine Methods Microscopy Mucociliary Clearance - physiology Mucus Mucus - metabolism Optical Coherence Tomography Pathology Physiology Primary Cell Culture Quantitative research Respiratory Mucosa - physiology Respiratory Mucosa - ultrastructure Respiratory tract Secretion Swine Tomography Tomography, Optical Coherence - instrumentation Tomography, Optical Coherence - methods
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