Differential evolutionary fate of an ancestral primate endogenous retrovirus envelope gene, the EnvV syncytin, captured for a function in placentation

Syncytins are envelope genes of retroviral origin that have been co-opted for a role in placentation. They promote cell-cell fusion and are involved in the formation of a syncytium layer--the syncytiotrophoblast--at the materno-fetal interface. They were captured independently in eutherian mammals,...

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Veröffentlicht in:PLoS genetics 2013-03, Vol.9 (3), p.e1003400-e1003400
Hauptverfasser: Esnault, Cécile, Cornelis, Guillaume, Heidmann, Odile, Heidmann, Thierry
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Sprache:eng
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