Slug controls stem/progenitor cell growth dynamics during mammary gland morphogenesis

Morphogenesis results from the coordination of distinct cell signaling pathways controlling migration, differentiation, apoptosis, and proliferation, along stem/progenitor cell dynamics. To decipher this puzzle, we focused on epithelial-mesenchymal transition (EMT) "master genes". EMT has...

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Veröffentlicht in:	PloS one 2012-12, Vol.7 (12), p.e53498-e53498
Hauptverfasser:	Nassour, Mayssa, Idoux-Gillet, Ysia, Selmi, Abdelkader, Côme, Christophe, Faraldo, Maria-Luisa M, Deugnier, Marie-Ange, Savagner, Pierre
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Animals Apoptosis Basal cells Biology Breast cancer Cadherins Cancer Cell Adhesion Cell cycle Cell Differentiation Cell lineage Cell migration Cell Movement Cell Proliferation Cellular Biology Cellular signal transduction Cycles Development Biology Differentiation (biology) Dynamics Epithelial cells Epithelial Cells - cytology Epithelial Cells - metabolism Epithelial-Mesenchymal Transition Epithelium Experiments Female GATA-3 protein Genes Genetic engineering Genotype & phenotype Growth Life Sciences Localization Mammary gland Mammary Glands, Animal - cytology Mammary Glands, Animal - embryology Mammary Glands, Animal - metabolism Medical research Mesenchyme Mice Morphogenesis Physiological aspects Physiology Progenitor cells Puberty Rodents Signaling Snail Family Transcription Factors Snail protein Stem cells Transcription factors Transcription Factors - genetics Transcription Factors - metabolism Transplantation
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