Chimeric infectious bursal disease virus-like particles as potent vaccines for eradication of established HPV-16 E7-dependent tumors

Cervical cancer is caused by persistent high-risk human papillomavirus (HR-HPV) infection and represents the second most frequent gynecological malignancy in the world. The HPV-16 type accounts for up to 55% of all cervical cancers. The HPV-16 oncoproteins E6 and E7 are necessary for induction and m...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	PloS one 2012-12, Vol.7 (12), p.e52976-e52976
Hauptverfasser:	Martin Caballero, Juan, Garzón, Ana, González-Cintado, Leticia, Kowalczyk, Wioleta, Jimenez Torres, Ignacio, Calderita, Gloria, Rodriguez, Margarita, Gondar, Virgínia, Bernal, Juan Jose, Ardavín, Carlos, Andreu, David, Zürcher, Thomas, von Kobbe, Cayetano
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antigen (tumor-associated) Antigens Biology Biomedical research Cancer Cancer immunotherapy Cancer treatment Cancer vaccines Cervical cancer Cervix Cytotoxicity Càncer Dendritic cells Deoxyribonucleic acid DNA E7 protein Female Genetic engineering Health risks Health sciences Histocompatibility antigen HLA HLA antigens Human papillomavirus Human papillomavirus 16 - immunology Immune response Immune system Immunology Immunotherapy Infectious bursal disease Infectious bursal disease virus - immunology Infectious diseases Laboratory animals Lymphocytes T Malalties Malignancy Medical research Medicine Mice Mice, Transgenic Oncology Papillomavirus E7 Proteins - immunology Papillomavirus infections Papillomavirus Infections - immunology Papillomavirus Infections - therapy Papillomavirus Vaccines - immunology Papillomavirus Vaccines - therapeutic use Papil·lomavirus Peptides Proteins T cells Transformation Transgenic mice Tumor cells Tumors Uterine Cervical Neoplasms - immunology Uterine Cervical Neoplasms - therapy Uterine Cervical Neoplasms - virology Vaccines Vaccines, Virus-Like Particle - immunology Vaccines, Virus-Like Particle - therapeutic use Virology Virus-like particles Viruses Úter
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!