Significance of the identification in the Horn of Africa of an exceptionally deep branching Mycobacterium tuberculosis clade

Molecular and phylogeographic studies have led to the definition within the Mycobacterium tuberculosis complex (MTBC) of a number of geotypes and ecotypes showing a preferential geographic location or host preference. The MTBC is thought to have emerged in Africa, most likely the Horn of Africa, and...

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Veröffentlicht in:	PloS one 2012-12, Vol.7 (12), p.e52841-e52841
Hauptverfasser:	Blouin, Yann, Hauck, Yolande, Soler, Charles, Fabre, Michel, Vong, Rithy, Dehan, Céline, Cazajous, Géraldine, Massoure, Pierre-Laurent, Kraemer, Philippe, Jenkins, Akinbowale, Garnotel, Eric, Pourcel, Christine, Vergnaud, Gilles
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Animals Biochemistry, Molecular Biology Biology Cluster Analysis Clustering Djibouti Ecotypes Gene sequencing Genes, Bacterial Genetic diversity Genetic factors Genomes Genomics Genotype Host preferences Humans Hypotheses Kenya Life Sciences Microbiology and Parasitology Migration Minisatellite Repeats Models, Genetic Multilocus Sequence Typing Mutation Mycobacterium Mycobacterium tuberculosis Mycobacterium tuberculosis - genetics Mycobacterium tuberculosis - isolation & purification Phylogeny Phylogeography Polymorphism, Single Nucleotide Population Somalia Spoligotyping Sudan Tuberculosis Tuberculosis - microbiology
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