Identification of epigenetically altered genes in sporadic amyotrophic lateral sclerosis

Amyotrophic lateral sclerosis (ALS) is a terminal disease involving the progressive degeneration of motor neurons within the motor cortex, brainstem and spinal cord. Most cases are sporadic (sALS) with unknown causes suggesting that the etiology of sALS may not be limited to the genotype of patients...

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Veröffentlicht in:PloS one 2012-12, Vol.7 (12), p.e52672-e52672
Hauptverfasser: Figueroa-Romero, Claudia, Hur, Junguk, Bender, Diane E, Delaney, Colin E, Cataldo, Michael D, Smith, Andrea L, Yung, Raymond, Ruden, Douglas M, Callaghan, Brian C, Feldman, Eva L
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