HMGB1 is associated with atherosclerotic plaque composition and burden in patients with stable coronary artery disease

The role of inflammation in atherosclerosis is widely appreciated. High mobility group box 1 (HMGB1), an injury-associated molecular pattern molecule acting as a mediator of inflammation, has recently been implicated in the development of atherosclerosis. In this study, we sought to investigate the...

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Veröffentlicht in:	PloS one 2012-12, Vol.7 (12), p.e52081-e52081
Hauptverfasser:	Andrassy, Martin, Volz, H Christian, Maack, Bjoern, Schuessler, Alena, Gitsioudis, Gitsios, Hofmann, Nina, Laohachewin, Danai, Wienbrandt, Alexandra R, Kaya, Ziya, Bierhaus, Angelika, Giannitsis, Evangelos, Katus, Hugo A, Korosoglou, Grigorios
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute coronary syndromes Aged Angina pectoris Angiography Arteriosclerosis Atherosclerosis Biology Biomarkers C-Reactive Protein Calcification Calcification (ectopic) Calcinosis - etiology Calcium-binding protein Cardiac patients Cardiology Cardiovascular disease Cardiovascular diseases Care and treatment CAT scans Chromosomal proteins Computed tomography Coronary Angiography Coronary artery Coronary artery disease Coronary Artery Disease - blood Coronary Artery Disease - diagnostic imaging Coronary Artery Disease - etiology Coronary heart disease Coronary vessels Development and progression Female Health risk assessment Health risks Heart attacks Heart diseases Heart rate HMGB1 protein HMGB1 Protein - blood Humans Inflammation Male Medical imaging Medical research Medicine Middle Aged Multivariate analysis Patients Plaque, Atherosclerotic - blood Plaque, Atherosclerotic - diagnostic imaging Plaque, Atherosclerotic - etiology Plaques Predictions Prognosis Proteins Risk analysis Risk factors Studies Tomography, X-Ray Computed Troponin Troponin T Troponin T - blood
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