Flagella from five Cronobacter species induce pro-inflammatory cytokines in macrophage derivatives from human monocytes

Cronobacter spp. are opportunistic pathogens linked to lie-threatening infections in neonates and contaminated powdered infant formula that has been epidemiologically associated with these cases. Clinical symptoms of Cronobacter include necrotizing enterocolitis, bacteremia, and meningitis. Flagella...

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Veröffentlicht in:	PloS one 2012-12, Vol.7 (12), p.e52091-e52091
Hauptverfasser:	Cruz-Córdova, Ariadnna, Rocha-Ramírez, Luz M, Ochoa, Sara A, González-Pedrajo, Bertha, Gónzalez-Pedrajo, Bertha, Espinosa, Norma, Eslava, Carlos, Hernández-Chiñas, Ulises, Mendoza-Hernández, Guillermo, Rodríguez-Leviz, Alejandra, Valencia-Mayoral, Pedro, Sadowinski-Pine, Stanislaw, Hernández-Castro, Rigoberto, Estrada-García, Iris, Muñoz-Hernández, Onofre, Rosas, Irma, Xicohtencatl-Cortes, Juan
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Antibodies Antibodies - immunology Antibodies - pharmacology Bacteremia Bacteria Biofilms Biology Cell activation Cronobacter Cronobacter - immunology Cronobacter - ultrastructure Cytokines Cytokines - metabolism Derivatives Dilution E coli Electron microscopy Enterocolitis Epidemiology Epithelial cells Escherichia coli Flagella Flagella - chemistry Flagella - drug effects Flagella - immunology Flagella - ultrastructure Flagellin Flagellin - chemistry Gel electrophoresis Gels Gene expression Health aspects HEK293 Cells Humans Immunoglobulin A Immunoglobulin A - immunology Immunoglobulin A - pharmacology Infections Inflammation Inflammation Mediators - metabolism Inflammatory response Interleukin 10 Interleukin 8 Macrophages Macrophages - cytology Macrophages - immunology Macrophages - metabolism Mass spectrometry Mass spectroscopy Medicine Meningitis Molecular Sequence Data Monocytes Monocytes - cytology Monomers Necrotizing enterocolitis Neonates Opportunist infection Pathogenesis Pathogens Peptides Rodents Salmonella Sequence Alignment Sodium lauryl sulfate TLR5 protein Toll-Like Receptor 5 - antagonists & inhibitors Toll-Like Receptor 5 - immunology Toll-like receptors Transfection Transmission electron microscopy Tumor necrosis factor
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