Energy efficient neural stimulation: coupling circuit design and membrane biophysics

The delivery of therapeutic levels of electrical current to neural tissue is a well-established treatment for numerous indications such as Parkinson's disease and chronic pain. While the neuromodulation medical device industry has experienced steady clinical growth over the last two decades, mu...

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Veröffentlicht in:	PloS one 2012-12, Vol.7 (12), p.e51901-e51901
Hauptverfasser:	Foutz, Thomas J, Ackermann, Jr, D Michael, Kilgore, Kevin L, McIntyre, Cameron C
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Axons - physiology Batteries Biology Biomedical engineering Biophysics Chronic pain Circuit design Circuits Computer simulation Electric potential Electric Stimulation Electrodes Energy conservation Energy consumption Energy efficiency Energy loss Energy management Energy use Engineering Experiments Health aspects Humans Medical devices Medical equipment Medicine Membrane Potentials Nerve Tissue - physiology Neuromodulation Pain Parkinson's disease Physics Power consumption Power efficiency Prostheses and implants Pulse generators Rats Sciatic Nerve - physiology Spinal cord Statistical analysis Stimulation Studies Transistors Voltage Waveforms
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