Folate metabolism gene 5,10-methylenetetrahydrofolate reductase (MTHFR) is associated with ADHD in myelomeningocele patients

The objective of this study was to examine the relation between the 5, 10-methylenetetrahydrofolate reductase (MTHFR) gene and behaviors related to attention- deficit/hyperactivity disorder (ADHD) in individuals with myelomeningocele. The rationale for the study was twofold: folate metabolizing gene...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	PloS one 2012-12, Vol.7 (12), p.e51330-e51330
Hauptverfasser:	Spellicy, Catherine J, Northrup, Hope, Fletcher, Jack M, Cirino, Paul T, Dennis, Maureen, Morrison, Alanna C, Martinez, Carla A, Au, Kit Sing
Format:	Artikel
Sprache:	eng
Schlagworte:	5, 10-Methylenetetrahydrofolate reductase (FADH2) Amino acids Attention Deficit Disorder with Hyperactivity - complications Attention Deficit Disorder with Hyperactivity - enzymology Attention Deficit Disorder with Hyperactivity - genetics Attention deficit hyperactivity disorder Behavior Biology Cardiovascular disease Case-Control Studies Child Children Chromosomes Cognitive ability Defects Deoxyribonucleic acid Development and progression Dihydrofolate reductase DNA DNA methylation Dopamine Enzymes Etiology Female Folic acid Folic Acid - metabolism Gene Frequency - genetics Genes Genetic Association Studies Genetic Predisposition to Disease Genome, Human - genetics Genomes Haplotypes - genetics Hispanic or Latino - genetics Homocysteine Humans Hyperactivity Leukemia Linkage Disequilibrium - genetics Male Medical research Medicine Meningomyelocele Meningomyelocele - complications Meningomyelocele - enzymology Meningomyelocele - genetics Metabolic Networks and Pathways - genetics Metabolism Metabolites Methylenetetrahydrofolate reductase Methylenetetrahydrofolate Reductase (NADPH2) - genetics Neural tube defects Patients Pediatrics Physiological aspects Polymorphism, Single Nucleotide - genetics Population Public health Science Single nucleotide polymorphisms Single-nucleotide polymorphism Social and Behavioral Sciences Spina bifida Studies Vitamin B White People - genetics
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!