High CCR5 density on central memory CD4+ T cells in acute HIV-1 infection is mostly associated with rapid disease progression

CD4+ central memory T cells play a critical role in the pathogenesis of simian immunodeficiency virus disease, and the CCR5 density on the surface of CD4 T cells is an important factor in human immunodeficiency virus (HIV)-1 disease progression. We hypothesized that quantifying central memory cells...

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Veröffentlicht in:PloS one 2012-11, Vol.7 (11), p.e49526-e49526
Hauptverfasser: Yang, Xue, Jiao, Yan-mei, Wang, Rui, Ji, Yun-xia, Zhang, Hong-wei, Zhang, Yong-hong, Chen, De-xi, Zhang, Tong, Wu, Hao
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Sprache:eng
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